RT Journal Article
SR Electronic
T1 Assessment of Platelet Inhibition by Point-of-Care Testing in Neuroendovascular Procedures
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 700
OP 706
DO 10.3174/ajnr.A2963
VO 34
IS 4
A1 H.M. Hussein
A1 T. Emiru
A1 A.L. Georgiadis
A1 A.I. Qureshi
YR 2013
UL http://www.ajnr.org/content/34/4/700.abstract
AB SUMMARY: Antiplatelet agents are an important component of the preventive strategies currently used in clinical practice to minimize the risk of thromboembolic events during and after endovascular procedures. Because of the variability in the response to antiplatelet agents, measuring the degree of platelet inhibition may help identify and properly treat poor responders. POC testing is defined as diagnostic testing at or near the site of patient care. Knowledge of the specifics of these devices among practicing neurointerventionalists is relatively limited. In this article, the different POC devices available are presented, and their clinical utility in relation to endovascular procedures is discussed. ADPadenosine diphosphateAMPadenosine monophosphateARUaspirin reaction unitBASEbaselineCADPcollagen/ADP test cartridgeCEPIcollagen/epinephrine test cartridgeCIconfidence intervalCITFcollagen-induced thrombus formationGP IIb/IIIaglycoprotein IIb/IIIaLTAlight-transmission aggregometryPARprotease-activated receptorsPAUplatelet aggregation unitsPCIpercutaneous coronary interventionPHTplatelet hemostasis timePOCpoint-of-carePRUP2Y12 reaction units