PT  - JOURNAL ARTICLE
AU  - S. Fau
AU  - C. Po
AU  - C. Goyenvalle
AU  - P. Meric
AU  - C. Charriaut-Marlangue
TI  - Do Early MRI Signals Predict Lesion Size in a Neonatal Stroke Rat Model?
AID  - 10.3174/ajnr.A3069
DP  - 2013 Jul 01
TA  - American Journal of Neuroradiology
PG  - E73--E76
VI  - 34
IP  - 7
4099  - http://www.ajnr.org/content/34/7/E73.short
4100  - http://www.ajnr.org/content/34/7/E73.full
SO  - Am. J. Neuroradiol.2013 Jul 01; 34
AB  - SUMMARY: In this study, we compared lesion size by using VADC and VT2 at 0, 2, 5, 24, and 48 hours and histologic lesions at 48 hours in a P7 rat stroke model. The best correlation between VHISTO and VADC was at H0, and between VHISTO and VT2, at H2-H5. Early MR imaging signals allowed excluding “no-lesion” and “no-reflow” animals to help standardize this neonatal stroke model and predict lesion size. H0, H2, H5, H24, and H4815 minutes and 2, 5, 24, and 48 hours after reperfusion, respectivelyP77-day-oldRARErapid acquisition relaxation excitementVADCvolume of lesion on ADC mapsVHISTOvolume of lesion on histologic sectionsVT2volume of lesion on T2 maps