PT - JOURNAL ARTICLE AU - Tomura, N. AU - Ito, Y. AU - Matsuoka, H. AU - Saginoya, T. AU - Numazawa, S.-i. AU - Mizuno, Y. AU - Watanabe, K. TI - PET Findings of Intramedullary Tumors of the Spinal Cord Using [<sup>18</sup>F] FDG and [<sup>11</sup>C] Methionine AID - 10.3174/ajnr.A3374 DP - 2013 Jun 01 TA - American Journal of Neuroradiology PG - 1278--1283 VI - 34 IP - 6 4099 - http://www.ajnr.org/content/34/6/1278.short 4100 - http://www.ajnr.org/content/34/6/1278.full SO - Am. J. Neuroradiol.2013 Jun 01; 34 AB - BACKGROUND AND PURPOSE: Only a few reports on intramedullary tumors of the spinal cord using PET have been published. We report findings of PET by using [18F] fluorodeoxyglucose and [11C] methionine and discuss the usefulness of the findings in patients with intramedullary tumors of the spinal cord. MATERIALS AND METHODS: PET/CT was performed in 9 patients with intramedullary tumors of the spinal cord: Six had ependymomas, 1 had an anaplastic astrocytoma, 1 had a hemangioblastoma, and 1 had a cavernous angioma. The maximum standardized uptake value of the tumor was measured and compared with pathologic findings. RESULTS: The SUVmax of FDG and MET in a case of anaplastic astrocytoma was high. The SUVmax of FDG and MET was relatively high in 4 of 6 cases of ependymoma (excluding myxopapillary ependymomas). A case of hemangioblastoma showed decreased uptake of both FDG and MET (SUVmax = 2.0 and 1.4, respectively). Three cases with hemorrhage (1 case of ependymoma, 1 case of cellular ependymoma, and 1 case of cavernous angioma) showed a relatively increased uptake of FDG. CONCLUSIONS: Both FDG and MET accumulated to a large degree in an anaplastic astrocytoma and accumulated in ependymomas (excluding a myxopapillary ependymoma). FDG can accumulate in tumors with hemorrhage. More investigation of a larger number of patients is required to evaluate the diagnostic value of PET with FDG and MET for imaging intramedullary tumors of the spinal cord. [11C]carbon 11[18F]fluorine 18FDGfluorodeoxyglucoseMET11C methionineSUVmaxmaximum standardized uptake value