RT Journal Article
SR Electronic
T1 The Kety-Schmidt Technique for Quantitative Perfusion and Oxygen Metabolism Measurements in the MR Imaging Environment
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP E100
OP E102
DO 10.3174/ajnr.A3270
VO 34
IS 9
A1 J.J. Lee
A1 W.J. Powers
A1 C.B. Faulkner
A1 P.J. Boyle
A1 C.P. Derdeyn
YR 2013
UL http://www.ajnr.org/content/34/9/E100.abstract
AB SUMMARY: The Kety-Schmidt technique provides quantitative measurement of whole-brain CBF. CBF is measured as the area between the arterial and venous washout curves of a diffusible tracer. Oxygen extraction and metabolism may be calculated from arterial and venous samples. In this report, we present a method for performing these measurements in an MR imaging environment. This technique could be useful for validation of MR imaging methods of hemodynamic and metabolic measurements in humans. CMRO2cerebral metabolic rate for oxygen consumptionIMintramuscularlyNDIRnondispersive infraredOEFoxygen extraction fraction