TY - JOUR T1 - The Kety-Schmidt Technique for Quantitative Perfusion and Oxygen Metabolism Measurements in the MR Imaging Environment JF - American Journal of Neuroradiology JO - Am. J. Neuroradiol. SP - E100 LP - E102 DO - 10.3174/ajnr.A3270 VL - 34 IS - 9 AU - J.J. Lee AU - W.J. Powers AU - C.B. Faulkner AU - P.J. Boyle AU - C.P. Derdeyn Y1 - 2013/09/01 UR - http://www.ajnr.org/content/34/9/E100.abstract N2 - SUMMARY: The Kety-Schmidt technique provides quantitative measurement of whole-brain CBF. CBF is measured as the area between the arterial and venous washout curves of a diffusible tracer. Oxygen extraction and metabolism may be calculated from arterial and venous samples. In this report, we present a method for performing these measurements in an MR imaging environment. This technique could be useful for validation of MR imaging methods of hemodynamic and metabolic measurements in humans. CMRO2cerebral metabolic rate for oxygen consumptionIMintramuscularlyNDIRnondispersive infraredOEFoxygen extraction fraction ER -