PT  - JOURNAL ARTICLE
AU  - M.N. Rozenfeld
AU  - S.A. Ansari
AU  - A. Shaibani
AU  - E.J. Russell
AU  - P. Mohan
AU  - M.C. Hurley
TI  - Should Patients with Autosomal Dominant Polycystic Kidney Disease Be Screened for Cerebral Aneurysms?
AID  - 10.3174/ajnr.A3437
DP  - 2014 Jan 01
TA  - American Journal of Neuroradiology
PG  - 3--9
VI  - 35
IP  - 1
4099  - http://www.ajnr.org/content/35/1/3.short
4100  - http://www.ajnr.org/content/35/1/3.full
SO  - Am. J. Neuroradiol.2014 Jan 01; 35
AB  - SUMMARY: Autosomal dominant polycystic kidney disease is a genetic disorder affecting 1 in 1000 people worldwide and is associated with an increased risk of intracranial aneurysms. It remains unclear whether there is sufficient net benefit to screening this patient population for IA, considering recent developments in imaging and treatment and our evolving understanding of the natural history of unruptured aneurysms. There is currently no standardized screening protocol for IA in patients with ADPCKD. Our review of the literature focused on the above issues and presents our appraisal of the estimated value of screening for IA in the setting of ADPCKD. ADPCKDautosomal dominant polycystic kidney diseaseGFRglomerular filtration rateIAintracranial aneurysmQALYquality-adjusted life yearsTOFtime-of-flight