RT Journal Article
SR Electronic
T1 New Applications of Nanotechnology for Neuroimaging
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1246
OP 1253
DO 10.3174/ajnr.A3543
VO 35
IS 7
A1 Suffredini, G.
A1 East, J.E.
A1 Levy, L.M.
YR 2014
UL http://www.ajnr.org/content/35/7/1246.abstract
AB SUMMARY: Advances in nanotechnology have the potential to dramatically enhance the detection of neurologic diseases with targeted contrast agents and to facilitate the delivery of focused therapies to the central nervous system. We present the physicochemical rationale for their use, applications in animal models, and ongoing clinical trials using these approaches. We highlight advances in the use of nanoparticles applied to brain tumor imaging, tumor angiogenesis, neurodegeneration, grafted stem cells, and neuroprogenitor cells. amyloid betaAβNOnitric oxideNOSnitric oxide synthasePBCApoly(n-butyl cyanoacrylate)QDotsquantum dotsSPIOsuperparamagnetic iron oxide