PT - JOURNAL ARTICLE AU - P.C. Sanelli AU - J.B. Sykes AU - A.L. Ford AU - J.-M. Lee AU - K.D. Vo AU - D.K. Hallam TI - Imaging and Treatment of Patients with Acute Stroke: An Evidence-Based Review AID - 10.3174/ajnr.A3518 DP - 2014 Jun 01 TA - American Journal of Neuroradiology PG - 1045--1051 VI - 35 IP - 6 4099 - http://www.ajnr.org/content/35/6/1045.short 4100 - http://www.ajnr.org/content/35/6/1045.full SO - Am. J. Neuroradiol.2014 Jun 01; 35 AB - SUMMARY: Evidence-based medicine has emerged as a valuable tool to guide clinical decision-making, by summarizing the best possible evidence for both diagnostic and treatment strategies. Imaging plays a critical role in the evaluation and treatment of patients with acute ischemic stroke, especially those who are being considered for thrombolytic or endovascular therapy. Time from stroke-symptom onset to treatment is a strong predictor of long-term functional outcome after stroke. Therefore, imaging and treatment decisions must occur rapidly in this setting, while minimizing unnecessary delays in treatment. The aim of this review was to summarize the best available evidence for the diagnostic and therapeutic management of patients with acute ischemic stroke. DPMdiffusion-perfusion mismatchIAintra-arterialICHintracranial hemorrhager-proUKrecombinant prourokinaseTIMIThrombolysis in Myocardial Infarction