RT Journal Article SR Electronic T1 Gadolinium Contrast Agents for CNS Imaging: Current Concepts and Clinical Evidence JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology SP 2215 OP 2226 DO 10.3174/ajnr.A3917 VO 35 IS 12 A1 E. Kanal A1 K. Maravilla A1 H.A. Rowley YR 2014 UL http://www.ajnr.org/content/35/12/2215.abstract AB SUMMARY: The aim of this article was to review the properties of the various gadolinium-based contrast agents used for CNS imaging along with the clinical evidence and published data that highlight the impact these different properties can have on diagnostic performance. In addition, approaches to optimizing image acquisition that take into account the different properties of specific gadolinium-based contrast agents and an extensive review of the safety profiles of the various agents are presented. CEcontrast-enhancedCNRcontrast-to-noise ratioGBCAgadolinium-based contrast agentGdgadoliniumNSFnephrogenic systemic fibrosisrCBVrelative cerebral blood volumerCBFrelative cerebral blood flow