RT Journal Article SR Electronic T1 Uses of Nanoparticles for Central Nervous System Imaging and Therapy JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology SP 1293 OP 1301 DO 10.3174/ajnr.A1590 VO 30 IS 7 A1 Provenzale, J.M. A1 Silva, G.A. YR 2009 UL http://www.ajnr.org/content/30/7/1293.abstract AB SUMMARY: Applications of nanotechnology to medicine are leading to novel means of imaging living systems and of delivering therapy. Much nanotechnology research is focused on methods for imaging central nervous system functions and disease states. In this review, the principles of nanoparticle design and function are discussed with specific emphasis on applications to neuroradiology. In addition to innovative forms of imaging, this review describes therapeutic uses of nanoparticles, such as drug delivery systems, neuroprotection devices, and methods for tissue regeneration.