RT Journal Article SR Electronic T1 Major Complications of Percutaneous Embolization of Skull-Base Tumors JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology SP 179 OP 181 VO 20 IS 1 A1 Alfredo Casasco A1 Emmanuel Houdart A1 Alessandra Biondi A1 Harish S. Jhaveri A1 Denis Herbreteau A1 Armand Aymard A1 Jean-Jacques Merland YR 1999 UL http://www.ajnr.org/content/20/1/179.abstract AB Summary: The technique of direct intratumoral injection of permanent liquid polymerizing agent was initially described in 1994 and has evolved significantly with experience. We report complications that occurred in two patients during injection of Histoacryl and offer suggestions to prevent such complications in the future. In one patient, the glue settled in the right middle cerebral artery; in the second, the glue entered the left ophthalmic artery through a collateral branch. Although the fundamental injection technique has not changed, we suggest additional precautions and modifications to make this procedure a safer and more valuable element in the overall management of patients with difficult skull-base tumors.