PT  - JOURNAL ARTICLE
AU  - Topçu, Meral
AU  - Saatci, Isil
AU  - Apak, R. Anil
AU  - Söylemezoglu, Figen
AU  - Akçören, Zuhal
TI  - Leigh Syndrome in a 3-Year-Old Boy with Unusual Brain MR Imaging and Pathologic Findings
DP  - 2000 Jan 01
TA  - American Journal of Neuroradiology
PG  - 224--227
VI  - 21
IP  - 1
4099  - http://www.ajnr.org/content/21/1/224.short
4100  - http://www.ajnr.org/content/21/1/224.full
SO  - Am. J. Neuroradiol.2000 Jan 01; 21
AB  - Summary: We report unusual MR serial imaging and electron microscopy findings in a 3-year-old boy who had Leigh syndrome with cytochrome-c oxidase (cox) deficiency. The MR imaging findings included periventricular white matter involvement, posteroanterior progression, and extension through the corpus callosum and internal capsule; however, no basal ganglia or brain stem abnormality was found, which was suggestive of leukodystrophy. The most noteworthy findings were the cystic foci with contrast enhancement in the affected white matter.