RT Journal Article
SR Electronic
T1 Coexistent Holoprosencephaly and Chiari II Malformation
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1678
OP 1681
VO 20
IS 9
A1 Nancy Rollins
A1 Jeanne Joglar
A1 Jeffery Perlman
YR 1999
UL http://www.ajnr.org/content/20/9/1678.abstract
AB Summary: Chiari II malformations and holoprosencephaly have been considered to be brain malformations that differ with respect to teratogenic insult, embryologic mechanism, and morphology. We herein describe coexistent Chiari II malformation and holoprosencephaly that occurred in a viable infant. A review of the literature regarding Chiari II malformations and holoprosencephaly suggests that a disturbance to the mesenchyme in early embryologic life may be the cause of both malformations.