PT - JOURNAL ARTICLE AU - Sakurai, Hideyuki AU - Mitsuhashi, Norio AU - Hayakawa, Kazushige AU - Niibe, Hideo TI - Giant Cell Tumor of the Thoracic Spine Simulating Mediastinal Neoplasm DP - 1999 Oct 01 TA - American Journal of Neuroradiology PG - 1723--1726 VI - 20 IP - 9 4099 - http://www.ajnr.org/content/20/9/1723.short 4100 - http://www.ajnr.org/content/20/9/1723.full SO - Am. J. Neuroradiol.1999 Oct 01; 20 AB - Summary: A case of giant cell tumor of the thoracic spine simulating mediastinal neoplasm was identified on plain films, CT scans, MR images, and with scintigraphy. CT showed a hypervascular soft-tissue mass with shell-like calcification in the right upper mediastinum. MR imaging showed a collapse of the T1 vertebral body and a mass extending to the mediastinum. The mass had a low signal on T1-weighted MR images and a predominantly high signal on T2-weighted images with heterogeneity. Technetium-99m methylene diphosphonate bone scintigraphy showed intense uptake in both the T1 and marginal parts of the mediastinal mass. There was no accumulation of gallium-67 citrate, but 18-fluorine fluorodeoxyglucose positron emission tomography showed marked uptake. The variation in these imaging findings played an important role in the differential diagnosis of this uncommon mediastinal mass.