RT Journal Article SR Electronic T1 Giant Cell Tumor of the Thoracic Spine Simulating Mediastinal Neoplasm JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology SP 1723 OP 1726 VO 20 IS 9 A1 Hideyuki Sakurai A1 Norio Mitsuhashi A1 Kazushige Hayakawa A1 Hideo Niibe YR 1999 UL http://www.ajnr.org/content/20/9/1723.abstract AB Summary: A case of giant cell tumor of the thoracic spine simulating mediastinal neoplasm was identified on plain films, CT scans, MR images, and with scintigraphy. CT showed a hypervascular soft-tissue mass with shell-like calcification in the right upper mediastinum. MR imaging showed a collapse of the T1 vertebral body and a mass extending to the mediastinum. The mass had a low signal on T1-weighted MR images and a predominantly high signal on T2-weighted images with heterogeneity. Technetium-99m methylene diphosphonate bone scintigraphy showed intense uptake in both the T1 and marginal parts of the mediastinal mass. There was no accumulation of gallium-67 citrate, but 18-fluorine fluorodeoxyglucose positron emission tomography showed marked uptake. The variation in these imaging findings played an important role in the differential diagnosis of this uncommon mediastinal mass.