RT Journal Article
SR Electronic
T1 Magnetization Transfer Ratio Is Unable to Lateralize Epileptic Foci in Patients with Temporal Lobe Epilepsy
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1853
OP 1856
VO 21
IS 10
A1 Li, Li Min
A1 Narayanan, Sridar
A1 Pike, Gilbert Bruce
A1 Andermann, Frederick
A1 Dubeau, François
A1 Arnold, Douglas L.
YR 2000
UL http://www.ajnr.org/content/21/10/1853.abstract
AB BACKGROUND AND PURPOSE: A preliminary report suggested that magnetization transfer ratio (MTR) was useful to lateralize epileptic foci in patients with refractory temporal lobe epilepsy (TLE). We attempted to confirm this finding in a larger group by investigating the relationship between MTR of mesial temporal structures and seizure lateralization in patients with refractory TLE.METHODS: We compared the MTR of amygdalae and hippocampi of 10 patients with unilateral TLE to values obtained from 10 healthy control participants.RESULTS: Three of 10 patients with TLE had MTR values that were 2 SD below the normal mean; the MTR abnormality was concordant with electroclinical lateralization in only one of the three.CONCLUSION: We conclude that MTR measurements of amygdalae and hippocampi are not useful for lateralization of TLE.