PT  - JOURNAL ARTICLE
AU  - Blustajn, Jerry
AU  - Netchine, Irène
AU  - Frédy, Daniel
AU  - Bakouche, Pierre
AU  - Piekarski, Jean Daniel
AU  - Meder, Jean François
TI  - Dysgenesis of the Internal Carotid ArteryAssociated with Transsphenoidal Encephalocele:A Neural Crest Syndrome?
DP  - 1999 Jun 01
TA  - American Journal of Neuroradiology
PG  - 1154--1157
VI  - 20
IP  - 6
4099  - http://www.ajnr.org/content/20/6/1154.short
4100  - http://www.ajnr.org/content/20/6/1154.full
SO  - Am. J. Neuroradiol.1999 Jun 01; 20
AB  - Summary: We describe two original cases of internal carotid artery dysgenesis associated with a malformative spectrum, which includes transsphenoidal encephalocele, optic nerve coloboma, hypopituitarism, and hypertelorism. Cephalic neural crest cells migrate to various regions in the head and neck where they contribute to the development of structures as diverse as the anterior skull base, the walls of the craniofacial arteries, the forebrain, and the face. Data suggest that the link between these rare malformations is abnormal neural crest development.