RT Journal Article SR Electronic T1 Triple-Technique (MR Imaging, Single-Photon Emission CT, and CT) Coregistration for Image-Guided Surgical Evaluation of Patients with Intractable Epilepsy JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology SP 1054 OP 1058 VO 20 IS 6 A1 Hogan, R. Edward A1 Lowe, Val J. A1 Bucholz, Richard D. YR 1999 UL http://www.ajnr.org/content/20/6/1054.abstract AB Summary: Ictal and interictal single-photon emission CT (SPECT) play an increasingly important role in the surgical evaluation of patients with epilepsy. We present a method of coregistration of MR, SPECT, and CT images to correlate structural data (MR imaging), blood flow changes (SPECT), and location of subdural electrodes (CT) for patients undergoing image-guided surgical treatment of epilepsy. MR-SPECT root mean square (rms) mismatch distances were 2.1 to 2.5 mm, and MR-CT rms mismatch distances were 1.0 to 4.5 mm. Coregistration assisted in image-guided placement of subdural electrodes and in surgical resection of the suspected epileptogenic focus.