PT  - JOURNAL ARTICLE
AU  - Gosche, Karen M.
AU  - Mortimer, James A.
AU  - Smith, Charles D.
AU  - Markesbery, William R.
AU  - Snowdon, David A.
TI  - An Automated Technique for Measuring Hippocampal Volumes from MR Imaging Studies
DP  - 2001 Oct 01
TA  - American Journal of Neuroradiology
PG  - 1686--1689
VI  - 22
IP  - 9
4099  - http://www.ajnr.org/content/22/9/1686.short
4100  - http://www.ajnr.org/content/22/9/1686.full
SO  - Am. J. Neuroradiol.2001 Oct 01; 22
AB  - Summary: We describe an automated volumetric measure of the hippocampus obtained with software called the Knowledge-Guided MRI Analysis Program (KGMAP). Postmortem MR images from 56 participants in the Nun Study were used to validate the measure. KGMAP-determined volumes strongly correlated with those obtained with manual tracings and neurofibrillary pathologic findings of Alzheimer disease in the hippocampus. KGMAP provides a rapid and accurate estimate of hippocampal volume that is suitable for use in clinical practice.