PT  - JOURNAL ARTICLE
AU  - Steven C. Cramer
AU  - Keith C. Stegbauer
AU  - Alex Schneider
AU  - John Mukai
AU  - Kenneth R. Maravilla
TI  - Decreased Diffusion in Central Pontine Myelinolysis
DP  - 2001 Sep 01
TA  - American Journal of Neuroradiology
PG  - 1476--1479
VI  - 22
IP  - 8
4099  - http://www.ajnr.org/content/22/8/1476.short
4100  - http://www.ajnr.org/content/22/8/1476.full
SO  - Am. J. Neuroradiol.2001 Sep 01; 22
AB  - Summary: Two patients with central pontine myelinolysis (CPM) were studied with diffusion-weighted MR imaging 1 week after onset of tetraplegia. In both patients, affected white matter showed hyperintensity on diffusion-weighted images associated with a decrease in apparent diffusion coefficient (ADC) values. In one patient studied serially, ADC values normalized by 3 weeks after tetraplegia. Early in the clinical course, diagnosis of CPM can sometimes be difficult. Hyperintensity on diffusion-weighted images may therefore have diagnostic utility. Decreased lesional ADC values support the notion that CPM is a consequence of relative intracellular hypotonicity.