TY - JOUR T1 - Decreased Diffusion in Central Pontine Myelinolysis JF - American Journal of Neuroradiology JO - Am. J. Neuroradiol. SP - 1476 LP - 1479 VL - 22 IS - 8 AU - Steven C. Cramer AU - Keith C. Stegbauer AU - Alex Schneider AU - John Mukai AU - Kenneth R. Maravilla Y1 - 2001/09/01 UR - http://www.ajnr.org/content/22/8/1476.abstract N2 - Summary: Two patients with central pontine myelinolysis (CPM) were studied with diffusion-weighted MR imaging 1 week after onset of tetraplegia. In both patients, affected white matter showed hyperintensity on diffusion-weighted images associated with a decrease in apparent diffusion coefficient (ADC) values. In one patient studied serially, ADC values normalized by 3 weeks after tetraplegia. Early in the clinical course, diagnosis of CPM can sometimes be difficult. Hyperintensity on diffusion-weighted images may therefore have diagnostic utility. Decreased lesional ADC values support the notion that CPM is a consequence of relative intracellular hypotonicity. ER -