PT - JOURNAL ARTICLE AU - Hans Rolf Jäger AU - Adam D Waldman AU - Christopher Benton AU - Nicholas Fox AU - Jeremy Rees TI - Differential Chemosensitivity of Tumor Components in a Malignant Oligodendroglioma: Assessment with Diffusion-Weighted, Perfusion-Weighted, and Serial Volumetric MR Imaging DP - 2005 Feb 01 TA - American Journal of Neuroradiology PG - 274--278 VI - 26 IP - 2 4099 - http://www.ajnr.org/content/26/2/274.short 4100 - http://www.ajnr.org/content/26/2/274.full SO - Am. J. Neuroradiol.2005 Feb 01; 26 AB - Summary: We report the case of malignant oligodendroglioma in a 36-year-old man who underwent diffusion-weighted, perfusion-weighted, and volumetric MR imaging before and after PCV (procarbazine, CCNU, vincristine) chemotherapy. The tumor regions exhibiting a low apparent diffusion coefficient and increased relative cerebral blood volume showed a marked response to chemotherapy and dramatic decrease in volume, whereas the remaining tumor regions showed little change. Diffusion-weighted and perfusion-weighted MR imaging may be helpful in predicting chemosensitivity of glial tumors.