RT Journal Article
SR Electronic
T1 Differential Chemosensitivity of Tumor Components in a Malignant Oligodendroglioma: Assessment with Diffusion-Weighted, Perfusion-Weighted, and Serial Volumetric MR Imaging
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 274
OP 278
VO 26
IS 2
A1 Jäger, Hans Rolf
A1 Waldman, Adam D
A1 Benton, Christopher
A1 Fox, Nicholas
A1 Rees, Jeremy
YR 2005
UL http://www.ajnr.org/content/26/2/274.abstract
AB Summary: We report the case of malignant oligodendroglioma in a 36-year-old man who underwent diffusion-weighted, perfusion-weighted, and volumetric MR imaging before and after PCV (procarbazine, CCNU, vincristine) chemotherapy. The tumor regions exhibiting a low apparent diffusion coefficient and increased relative cerebral blood volume showed a marked response to chemotherapy and dramatic decrease in volume, whereas the remaining tumor regions showed little change. Diffusion-weighted and perfusion-weighted MR imaging may be helpful in predicting chemosensitivity of glial tumors.