TY - JOUR T1 - Differential Chemosensitivity of Tumor Components in a Malignant Oligodendroglioma: Assessment with Diffusion-Weighted, Perfusion-Weighted, and Serial Volumetric MR Imaging JF - American Journal of Neuroradiology JO - Am. J. Neuroradiol. SP - 274 LP - 278 VL - 26 IS - 2 AU - Hans Rolf Jäger AU - Adam D Waldman AU - Christopher Benton AU - Nicholas Fox AU - Jeremy Rees Y1 - 2005/02/01 UR - http://www.ajnr.org/content/26/2/274.abstract N2 - Summary: We report the case of malignant oligodendroglioma in a 36-year-old man who underwent diffusion-weighted, perfusion-weighted, and volumetric MR imaging before and after PCV (procarbazine, CCNU, vincristine) chemotherapy. The tumor regions exhibiting a low apparent diffusion coefficient and increased relative cerebral blood volume showed a marked response to chemotherapy and dramatic decrease in volume, whereas the remaining tumor regions showed little change. Diffusion-weighted and perfusion-weighted MR imaging may be helpful in predicting chemosensitivity of glial tumors. ER -