RT Journal Article
SR Electronic
T1 Diffusion Tensor Imaging in Lissencephaly
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1583
OP 1586
VO 26
IS 6
A1 Rollins, Nancy
A1 Reyes, Tony
A1 Chia, Jon
YR 2005
UL http://www.ajnr.org/content/26/6/1583.abstract
AB Summary: Lissencephaly is a rare brain malformation characterized histologically by arrested neuronal migration such that the brain resembles that of a fetus before 23–24 weeks gestation. We studied a neonate with lissencephaly by using diffusion tensor imaging and suggest the dysplastic densely cellular layer IV is visible as a band of anisotropic diffusion. Fiber tracking showed lack of connectivity between the cortex and deep white matter and an abnormal limbic system.