PT - JOURNAL ARTICLE AU - Dai, Daying AU - Ding, Yong Hong AU - Danielson, Mark A. AU - Kadirvel, Ramanathan AU - Lewis, Debra A. AU - Cloft, Harry J. AU - Kallmes, David F. TI - Modified Histologic Technique for Processing Metallic Coil-Bearing Tissue DP - 2005 Sep 01 TA - American Journal of Neuroradiology PG - 1932--1936 VI - 26 IP - 8 4099 - http://www.ajnr.org/content/26/8/1932.short 4100 - http://www.ajnr.org/content/26/8/1932.full SO - Am. J. Neuroradiol.2005 Sep 01; 26 AB - We developed a modified paraffin-embedding histologic technique for processing metallic coil-bearing aneurysm tissues. This modified technique was successfully employed for processing platinum coil-bearing tissue for 30 rabbit aneurysms and 6 swine aneurysms. This technique for sectioning coil-bearing aneurysms resulted in little or no tissue distortion and permitted good preservation of morphology and application of multiple advanced staining techniques. This technique is considered beneficial for studying the molecular mechanisms of aneurysm healing after coiling.