RT Journal Article
SR Electronic
T1 PET studies of glucose metabolism in patients with schizophrenia.
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 550
OP 552
VO 4
IS 3
A1 L Widen
A1 G Blomqvist
A1 T Greitz
A1 J E Litton
A1 M Bergström
A1 E Ehrin
A1 K Ericson
A1 L Eriksson
A1 D H Ingvar
A1 L Johansson
A1 J L Nilsson
A1 S Stone-Elander
A1 G Sedvall
A1 F Wiesel
A1 G Wiik
YR 1983
UL http://www.ajnr.org/content/4/3/550.abstract
AB The hypothesis of abnormal patterns of metabolism in schizophrenia was examined in a series of six young patients with psychotic symptoms satisfying the research diagnostic criteria. After intravenous injection of 11C-glucose obtained through a photosynthetic process, the regional activity of 11C in brain was measured with a four-ring positron camera. Regions of interest were obtained from computed tomographic images. Each patient underwent a second positron emission tomographic examinations after 4-5 weeks of treatment with a neuroleptic drug. No evidence of a hypofrontal pattern was found, but after treatment there was a reduced frontal uptake on the left side compared with temporal regions. The left-right asymmetry in the lentiform nucleus was reduced after treatment.