RT Journal Article SR Electronic T1 Quantification of gray/white matter in neonates and adults. JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology SP 692 OP 695 VO 4 IS 3 A1 Lee, B C A1 Kneeland, B A1 Knowles, R J A1 Cahill, P T YR 1983 UL http://www.ajnr.org/content/4/3/692.abstract AB Quantitation of gray/white matter is important in evaluation of cerebral blood flow, atrophy, and development of the brain. First-order statistical analysis of neonatal computed tomographic (CT) images revealed that there was only a 6 Hounsfield unit (H) difference between gray and white matter compared with the observed 3 H for the standard deviation over the field of a skull water phantom. Scene segmentation methods based on first-order statistics proved unsuccessful in separating gray and white matter. A new regional clustering algorithm based on local textural properties was developed for separation of these structures.