RT Journal Article SR Electronic T1 Persistent high MR signal of the posterior pituitary gland in central diabetes insipidus. JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology SP 1749 OP 1752 VO 18 IS 9 A1 M Maghnie A1 E Genovese A1 S Bernasconi A1 S Binda A1 M Aricò YR 1997 UL http://www.ajnr.org/content/18/9/1749.abstract AB We describe three cases of central diabetes insipidus, each with a different pathogenesis, in which unexpected hyperintensity of the posterior pituitary gland was seen on T1-weighted MR images obtained at the time of presentation. In the first case (idiopathic), the posterior pituitary signal persisted more than 10 years; in the second case (Langerhans cell histiocytosis), the signal disappeared within 3 months, despite early specific chemotherapy with etoposide; and in the third case (transient), the posterior signal disappeared within 1 year, but it was documented at the time of spontaneous reversal of polyuria and polydipsia.