PT  - JOURNAL ARTICLE
AU  - S Shintani
AU  - S Tsuruoka
AU  - T Shiigai
TI  - Paradoxical hyperfixation of hexamethylpropyleneamine oxime in cerebral infarction.
DP  - 1997 Nov 01
TA  - American Journal of Neuroradiology
PG  - 1905--1908
VI  - 18
IP  - 10
4099  - http://www.ajnr.org/content/18/10/1905.short
4100  - http://www.ajnr.org/content/18/10/1905.full
SO  - Am. J. Neuroradiol.1997 Nov 01; 18
AB  - We describe four patients with cerebral infarction and 99mTc-hexamethylpropyleneamine oxime (HMPAO) hyperfixation in distributions corresponding to the infarctions seen at CT and/or MR imaging. Increased HMPAO extraction due to hyperpermeability across the blood-brain barrier and increased retention due to reduced back diffusion of the tracer probably accounted for the increased fractional fixation in infarcts seen in our patients.