TY - JOUR T1 - Paradoxical hyperfixation of hexamethylpropyleneamine oxime in cerebral infarction. JF - American Journal of Neuroradiology JO - Am. J. Neuroradiol. SP - 1905 LP - 1908 VL - 18 IS - 10 AU - S Shintani AU - S Tsuruoka AU - T Shiigai Y1 - 1997/11/01 UR - http://www.ajnr.org/content/18/10/1905.abstract N2 - We describe four patients with cerebral infarction and 99mTc-hexamethylpropyleneamine oxime (HMPAO) hyperfixation in distributions corresponding to the infarctions seen at CT and/or MR imaging. Increased HMPAO extraction due to hyperpermeability across the blood-brain barrier and increased retention due to reduced back diffusion of the tracer probably accounted for the increased fractional fixation in infarcts seen in our patients. ER -