RT Journal Article
SR Electronic
T1 Paradoxical hyperfixation of hexamethylpropyleneamine oxime in cerebral infarction.
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1905
OP 1908
VO 18
IS 10
A1 S Shintani
A1 S Tsuruoka
A1 T Shiigai
YR 1997
UL http://www.ajnr.org/content/18/10/1905.abstract
AB We describe four patients with cerebral infarction and 99mTc-hexamethylpropyleneamine oxime (HMPAO) hyperfixation in distributions corresponding to the infarctions seen at CT and/or MR imaging. Increased HMPAO extraction due to hyperpermeability across the blood-brain barrier and increased retention due to reduced back diffusion of the tracer probably accounted for the increased fractional fixation in infarcts seen in our patients.