PT  - JOURNAL ARTICLE
AU  - T Yoshiura
AU  - K Hasuo
AU  - F Mihara
AU  - K Masuda
AU  - T Morioka
AU  - M Fukui
TI  - Increased activity of the ipsilateral motor cortex during a hand motor task in patients with brain tumor and paresis.
DP  - 1997 May 01
TA  - American Journal of Neuroradiology
PG  - 865--869
VI  - 18
IP  - 5
4099  - http://www.ajnr.org/content/18/5/865.short
4100  - http://www.ajnr.org/content/18/5/865.full
SO  - Am. J. Neuroradiol.1997 May 01; 18
AB  - PURPOSE To look for changes in the motor cortex in patients with brain tumors.METHODS Both cerebral hemispheres in seven patients with brain tumors were examined with functional MR imaging during a motor task performed by the hand opposite the site of tumor. The ratio of the activated area in the motor cortex ipsilateral/contralateral to the tested hand was calculated for each subject. Twenty healthy subjects were also examined in the same manner for comparison.RESULTS The ratio of the ipsilateral/contralateral activated area was abnormally high in three patients with tumor-related paresis of the tested hand. The ratio was significantly greater in patients with paresis than in healthy subjects.CONCLUSION This study demonstrated increased activity in the ipsilateral (unaffected) motor area during a hand motor task in patients with brain tumor and paresis, which was thought to reflect compensatory reorganization induced by the functional damage.