RT Journal Article
SR Electronic
T1 MR changes in the calcarine area resulting from retinal degeneration.
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1291
OP 1295
VO 18
IS 7
A1 M Kitajima
A1 Y Korogi
A1 T Hirai
A1 S Hamatake
A1 I Ikushima
A1 T Sugahara
A1 Y Shigematsu
A1 M Takahashi
A1 K Mukuno
YR 1997
UL http://www.ajnr.org/content/18/7/1291.abstract
AB PURPOSE To study MR images for atrophic changes in the calcarine area resulting from retinal degeneration.METHODS MR images from nine patients with retinal degeneration confirmed by ophthalmologic examination and from 30 healthy volunteers were reviewed. The causes of retinal degeneration were hereditary pigmentary degeneration of the retina (four patients), high myopia (two patients), and chorioretinal atrophy (three patients); all patients had visual disturbances and visual field abnormalities. To estimate the morphological changes of the calcarine area, the widths of the right and left calcarine fissures were measured on T1-weighted sagittal images and compared with images from age-matched control subjects.RESULTS The calcarine fissures were significantly dilated in the patients with retinal degeneration. The anterior and middle points, which represent the peripheral visual field center, were more dilated than the posterior point.CONCLUSION The MR findings suggested calcarine atrophy related to retinal degeneration. Transneuronal degenerative changes may occur in the calcarine area after retinal degeneration.