PT - JOURNAL ARTICLE AU - Brant-Zawadzki, M AU - Fein, G AU - Van Dyke, C AU - Kiernan, R AU - Davenport, L AU - de Groot, J TI - MR imaging of the aging brain: patchy white-matter lesions and dementia. DP - 1985 Sep 01 TA - American Journal of Neuroradiology PG - 675--682 VI - 6 IP - 5 4099 - http://www.ajnr.org/content/6/5/675.short 4100 - http://www.ajnr.org/content/6/5/675.full SO - Am. J. Neuroradiol.1985 Sep 01; 6 AB - Magnetic resonance (MR) imaging studies of the brain in five elderly patients with non-Alzheimer dementia were compared with those in two groups of nondemented control subjects. Group 1 included five subjects aged 59-66; group 2 included nine subjects aged 74-81. In all of the demented patients and in three of the subjects in the older control group, MR showed diffuse, patchy white-matter lesions. A rating scale was used to grade the severity of the changes. The results suggest a higher incidence of white-matter lesions in elderly patients with non-Alzheimer dementia and in cognitively normal elderly with advancing age.