PT - JOURNAL ARTICLE AU - Masucci, E F AU - Borts, F T AU - Smirniotopoulos, J G AU - Kurtzke, J F AU - Schellinger, D TI - Thin-section CT of midbrain abnormalities in progressive supranuclear palsy. DP - 1985 Sep 01 TA - American Journal of Neuroradiology PG - 767--772 VI - 6 IP - 5 4099 - http://www.ajnr.org/content/6/5/767.short 4100 - http://www.ajnr.org/content/6/5/767.full SO - Am. J. Neuroradiol.1985 Sep 01; 6 AB - Thin-section computed tomographic (CT) scans of 3 and 1.5 mm thickness were obtained using the Philips Tomoscan 310 and General Electric 8800 CT/T scanners in the study of 10 consecutive patients with progressive supranuclear palsy (PSP) and 31 patients with other diseases. Marked midbrain and moderate pontine atrophy, a dilated third ventricle, and enlarged quadrigeminal plate cisterns were observed in all PSP cases. The aqueduct was dilated in several. In six of the PSP cases, there was a striking midbrain abnormality in the form of a low-density area extending from the interpeduncular cistern toward the aqueduct. Thin-section metrizamide-enhanced cisternography of three of the six PSP cases showed that the low-density abnormality was the result of the interpeduncular cistern invaginating the atrophic midbrain.