RT Journal Article
SR Electronic
T1 MR findings in acute and chronic coccidioidomycosis meningitis.
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1241
OP 1245
VO 13
IS 4
A1 C J Wrobel
A1 S Meyer
A1 R H Johnson
A1 J R Hesselink
YR 1992
UL http://www.ajnr.org/content/13/4/1241.abstract
AB PURPOSE To characterize MR findings in acute and chronic coccidioidomycosis meningitis and relate the imaging features to the clinical course.METHODS We reviewed MR scans and clinical findings of 12 patients with coccidioidal meningitis.RESULTS Patients with active or untreated disease were found to have hydrocephalus and intense enhancement of the cervical subarachnoid space, basilar, sylvian, and interhemispheric cisterns on postcontrast MR scans. Focal parenchymal signal abnormalities suggesting ischemia or infarction were common. Abnormal MR enhancement decreases during therapy, although patients develop cortical and/or brain stem atrophy.CONCLUSIONS Widespread cisternal and cervical subarachnoid meningeal involvement is common in coccidioidal meningitis. Serial contrast MR imaging reflects the effects of therapy in patients with coccidioidal meningitis.