RT Journal Article
SR Electronic
T1 [<sup>18</sup>F]-Sodium Fluoride PET MR–Based Localization and Quantification of Bone Turnover as a Biomarker for Facet Joint–Induced Disability
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 2028
OP 2031
DO 10.3174/ajnr.A5348
VO 38
IS 10
A1 Jenkins, N.W.
A1 Talbott, J.F.
A1 Shah, V.
A1 Pandit, P.
A1 Seo, Y.
A1 Dillon, W.P.
A1 Majumdar, S.
YR 2017
UL http://www.ajnr.org/content/38/10/2028.abstract
AB SUMMARY: Our aim was to prospectively evaluate the relationship between low back pain–related disability and quantitative measures from [18F]-sodium fluoride ([18F]-NaF) MR imaging. Six patients with facetogenic low back pain underwent dynamic [18F]-NaF PET/MR imaging. PET metrics were correlated with clinical measures and MR imaging grading of lumbar facet arthropathy. A significant positive correlation was observed between maximum facet joint uptake rate and clinical disability (P &lt; .05). These data suggest that dynamic [18F]-NaF PET may serve as a useful biomarker for facetogenic disability.FJfacet jointIPAQInternational Physical Activity QuestionnairemaxmaximumminminimummL/ccm/minmilliliters/cubic centimeter/minuteODIOswestry Disability IndexSUVstandard uptake value