PT  - JOURNAL ARTICLE
AU  - S Halpin
AU  - D Kingsley
TI  - Disappearance of cerebral calcification as a sign of tumor growth.
DP  - 1993 Jan 01
TA  - American Journal of Neuroradiology
PG  - 119--122
VI  - 14
IP  - 1
4099  - http://www.ajnr.org/content/14/1/119.short
4100  - http://www.ajnr.org/content/14/1/119.full
SO  - Am. J. Neuroradiol.1993 Jan 01; 14
AB  - Calcification occurs in many benign and malignant neurologic disorders. We describe two patients with cerebral glioma, in whom the disappearance of cerebral calcification was evidence of local malignant change. We discuss the underlying chemical mechanisms that result in tissue calcification, and postulate that calcification may disappear in the presence of a malignant tumor because of a decrease in the pH of the microenvironment.