PT - JOURNAL ARTICLE AU - Castillo, M AU - Kwock, L AU - Scatliff, J AU - Gudeman, S AU - Greenwood, R TI - Proton MR spectroscopic characteristics of a presumed giant subcortical heterotopia. DP - 1993 Mar 01 TA - American Journal of Neuroradiology PG - 426--429 VI - 14 IP - 2 4099 - http://www.ajnr.org/content/14/2/426.short 4100 - http://www.ajnr.org/content/14/2/426.full SO - Am. J. Neuroradiol.1993 Mar 01; 14 AB - A newborn presented with a mass replacing the left cerebral hemisphere. Although the internal signal characteristics of the lesion were suggestive of disorganized gray and white matter, a true neoplasia such as a ganglioglioma could not be totally excluded. Biopsy is not recommended in these cases since the results may be misleading. Proton MR spectroscopy was used; this technique also suggested the hamartomatous nature of the lesion. Based on the clinical course and the imaging features, conservative therapy and observation were undertaken instead of surgery. At 6 months of age, the patient is stable and the lesion is unchanged.