RT Journal Article SR Electronic T1 Proton MR spectroscopic characteristics of a presumed giant subcortical heterotopia. JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology SP 426 OP 429 VO 14 IS 2 A1 Castillo, M A1 Kwock, L A1 Scatliff, J A1 Gudeman, S A1 Greenwood, R YR 1993 UL http://www.ajnr.org/content/14/2/426.abstract AB A newborn presented with a mass replacing the left cerebral hemisphere. Although the internal signal characteristics of the lesion were suggestive of disorganized gray and white matter, a true neoplasia such as a ganglioglioma could not be totally excluded. Biopsy is not recommended in these cases since the results may be misleading. Proton MR spectroscopy was used; this technique also suggested the hamartomatous nature of the lesion. Based on the clinical course and the imaging features, conservative therapy and observation were undertaken instead of surgery. At 6 months of age, the patient is stable and the lesion is unchanged.