RT Journal Article
SR Electronic
T1 Kallmann syndrome: MR findings.
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 845
OP 851
VO 14
IS 4
A1 J R Knorr
A1 R L Ragland
A1 R S Brown
A1 N Gelber
YR 1993
UL http://www.ajnr.org/content/14/4/845.abstract
AB PURPOSE To evaluate patients with known hypogonadotropic hypogonadism, some with known anosmia, for defective rhinocephalon development that resulted in olfactory tract abnormalities, an affliction known as Kallmann syndrome.METHODS Six patients who clinically had hypogonadotropic hypogonadism were examined by MR. Thin coronal images of the interior frontal region were used to determine presence or absence of olfactory tract and to evaluate the olfactory sulci.RESULTS Olfactory tracts were not seen in three of the six cases; two of which had hypoplastic olfactory sulci.CONCLUSIONS T1-weighted MR examination of the inferior frontal region in the coronal plane can help determine whether a patient with hypogonadotropic hypogonadism, with or without clinically evident anosmia, is afflicted with Kallmann syndrome.