PT - JOURNAL ARTICLE AU - S Choi AU - D R Enzmann TI - Infantile Krabbe disease: complementary CT and MR findings. DP - 1993 Sep 01 TA - American Journal of Neuroradiology PG - 1164--1166 VI - 14 IP - 5 4099 - http://www.ajnr.org/content/14/5/1164.short 4100 - http://www.ajnr.org/content/14/5/1164.full SO - Am. J. Neuroradiol.1993 Sep 01; 14 AB - This case report of the infantile form of Krabbe disease in a 2 1/2-month-old boy illustrates the complementary findings that may be seen on CT and MR scans. The key finding on the CT scan was increased density in a bilateral symmetrical distribution involving the thalami with extension into the centrum semiovale. The MR scan, on the other hand, more clearly showed demyelination in the brain stem and cerebellum. In cases in which this involvement is minimal or absent, the MR scan may fail to detect an abnormality, and a CT scan will, therefore, still be necessary to detect characteristic abnormalities.