PT  - JOURNAL ARTICLE
AU  - J Lee
AU  - D Lacomis
AU  - S Comu
AU  - J Jacobsohn
AU  - E Kanal
TI  - Acquired hepatocerebral degeneration: MR and pathologic findings.
DP  - 1998 Mar 01
TA  - American Journal of Neuroradiology
PG  - 485--487
VI  - 19
IP  - 3
4099  - http://www.ajnr.org/content/19/3/485.short
4100  - http://www.ajnr.org/content/19/3/485.full
SO  - Am. J. Neuroradiol.1998 Mar 01; 19
AB  - Acquired (non-Wilsonian) hepatocerebral degeneration (AHD) is a rare irreversible neurologic syndrome that occurs in patients with chronic liver disease associated with multiple metabolic insults. The pathophysiology and the locations of the cerebral injuries are incompletely understood. We describe a patient with fatal hepatic cirrhosis and AHD in whom MR images showed abnormalities in the brachium pontis bilaterally. Neuropathologic evaluation disclosed multiple regions of subcortical spongiform white matter changes.