RT Journal Article SR Electronic T1 Deep Learning in Neuroradiology JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology SP 1776 OP 1784 DO 10.3174/ajnr.A5543 VO 39 IS 10 A1 G. Zaharchuk A1 E. Gong A1 M. Wintermark A1 D. Rubin A1 C.P. Langlotz YR 2018 UL http://www.ajnr.org/content/39/10/1776.abstract AB SUMMARY: Deep learning is a form of machine learning using a convolutional neural network architecture that shows tremendous promise for imaging applications. It is increasingly being adapted from its original demonstration in computer vision applications to medical imaging. Because of the high volume and wealth of multimodal imaging information acquired in typical studies, neuroradiology is poised to be an early adopter of deep learning. Compelling deep learning research applications have been demonstrated, and their use is likely to grow rapidly. This review article describes the reasons, outlines the basic methods used to train and test deep learning models, and presents a brief overview of current and potential clinical applications with an emphasis on how they are likely to change future neuroradiology practice. Facility with these methods among neuroimaging researchers and clinicians will be important to channel and harness the vast potential of this new method.ADAlzheimer diseaseADNIAlzheimer's Disease Neuroimaging InitiativeASLarterial spin-labelingCNNconvolutional neural networkMCImild cognitive impairmentNCnormal control