PT - JOURNAL ARTICLE AU - Bourcier, R. AU - Derraz, I. AU - Bracard, S. AU - Oppenheim, C. AU - Naggara, O. ED - TI - Two-Layered Susceptibility Vessel Sign and High Overestimation Ratio on MRI Are Predictive of Cardioembolic Stroke AID - 10.3174/ajnr.A5865 DP - 2019 Jan 01 TA - American Journal of Neuroradiology PG - 65--67 VI - 40 IP - 1 4099 - http://www.ajnr.org/content/40/1/65.short 4100 - http://www.ajnr.org/content/40/1/65.full SO - Am. J. Neuroradiol.2019 Jan 01; 40 AB - SUMMARY: In a prospective study among patients in the THRombectomie des Artères Cerebrales trial, we analyzed the diagnostic accuracy of 2 imaging biomarkers, the 2-layered susceptibility vessel sign and a high overestimation ratio, obtained on pretreatment brain T2* sequences, to identify cardioembolic stroke etiology (107/260 patients). In combination, these 2 biomarkers, on 1.5T or 3T systems (159 and 101 patients, respectively), demonstrated high specificity (0.77 at 1.5T and 1 at 3T) and their simultaneous presence is highly associated with cardioembolism.CEScardioembolic strokeHORhigh overestimation ratioNPVnegative predictive valueoverRoverestimation ratioPPVpositive predictive valueSVSsusceptibility vessel signTHRACETHRombectomie des Artères CerebralesTL-SVS2-layered susceptibility vessel sign