PT  - JOURNAL ARTICLE
AU  - Ginestroni, A.
AU  - Guerrini, L.
AU  - Nave, R. Della
AU  - Tessa, C.
AU  - Cellini, E.
AU  - Dotti, M.T.
AU  - Brunori, P.
AU  - De Stefano, N.
AU  - Piacentini, S.
AU  - Mascalchi, M.
TI  - Morphometry and <sup>1</sup>H-MR Spectroscopy of the Brain Stem and Cerebellum in Three Patients with Fragile X-Associated Tremor/Ataxia Syndrome
DP  - 2007 Mar 01
TA  - American Journal of Neuroradiology
PG  - 486--488
VI  - 28
IP  - 3
4099  - http://www.ajnr.org/content/28/3/486.short
4100  - http://www.ajnr.org/content/28/3/486.full
SO  - Am. J. Neuroradiol.2007 Mar 01; 28
AB  - SUMMARY: Morphometry and spectroscopy were performed in 3 patients with fragile X-associated tremor/ataxia syndrome (FXTAS). The brain stem and cerebellum were atrophic and satisfied criteria for olivopontocerebellar atrophy in 2 patients. However, the vermis was relatively spared and the basis pontis maintained its oval shape. The only spectroscopic abnormality was a decrease of the pontine N-acetylaspartate/creatine ratio in 1 patient. Atrophy and metabolic changes in FXTAS differ to some extent from those of olivopontocerebellar atrophy.