PT  - JOURNAL ARTICLE
AU  - Mascalchi, M.
AU  - Gavazzi, C.
AU  - Morbin, M.
AU  - Giaccone, G.
AU  - Arnetoli, G.
AU  - Zappoli, R.
AU  - Bugiani, O.
TI  - CT and MR Imaging of Neuroaxonal Leukodystrophy Presenting as Early-Onset Frontal Dementia
DP  - 2006 May 01
TA  - American Journal of Neuroradiology
PG  - 1037--1039
VI  - 27
IP  - 5
4099  - http://www.ajnr.org/content/27/5/1037.short
4100  - http://www.ajnr.org/content/27/5/1037.full
SO  - Am. J. Neuroradiol.2006 May 01; 27
AB  - SUMMARY: CT and MR imaging showed diffuse changes of the frontal white matter and genu of the corpus callosum with minimal atrophy and no contrast enhancement in a 41-year-old woman with progressive dementia. Brain biopsy disclosed axonal spheroids and gliosis in the white matter without macrophage or inflammatory infiltration or vessel abnormalities consistent with neuroaxonal leukodystrophy. This disease can be suspected on CT and MR imaging findings but requires neuropathologic examination to be diagnosed.