RT Journal Article
SR Electronic
T1 Underestimation of Cerebral Perfusion on Flow-Sensitive Alternating Inversion Recovery Image: Semiquantitative Evaluation with Time-to-Peak Values
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 2008
OP 2013
DO 10.3174/ajnr.A0720
VO 28
IS 10
A1 H.S. Kim
A1 S.Y. Kim
A1 J.M. Kim
YR 2007
UL http://www.ajnr.org/content/28/10/2008.abstract
AB BACKGROUND AND PURPOSE: We assessed the underestimation of cerebral perfusion measured by the flow-sensitive alternating inversion recovery (FAIR) technique in patients with carotid stenosis and compared the technique with dynamic susceptibility contrast (DSC) MR images.MATERIALS AND METHODS: We studied 42 areas of decreased cerebral blood flow (CBF) using 3 FAIR images with different inversion times (TIs) in 42 consecutive patients with unilateral carotid stenosis of more than 50%. The width of decreased CBF area (wCBF) was qualitatively assessed. We analyzed the ratio of CBF (rCBF) and the time-to-peak (TTP) difference (dTTP) between the ipsilateral hemisphere to carotid stenosis and contralateral normal area using regions of interest (ROIs) at the same location.RESULTS: In the areas with more prolonged TTP (dTTP ≥3.2 s), the wCBF obtained from the FAIR images with TI of 1600 ms was smaller than those from the FAIR images with a TI of 800 ms and 1200 ms in all cases. The mean rCBF obtained from the FAIR images with a TI of 1200 ms was significantly lower than that obtained from the FAIR images with a TI of 1600 ms (P < .01) in the areas with more prolonged TTP. In the areas with less prolonged TTP (dTTP <3.2 s), the wCBF and mean rCBF were not significantly different between the 2 FAIR images (TI, 1200 and 1600 ms).CONCLUSION: If TTP is delayed significantly (dTTP ≥3.2 s), the FAIR with intermediate or short TI showed underestimation of perfusion in the same area with delay in TTP.