RT Journal Article
SR Electronic
T1 Susceptibility-Weighted Imaging: Technical Aspects and Clinical Applications, Part 1
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 19
OP 30
DO 10.3174/ajnr.A1400
VO 30
IS 1
A1 Haacke, E.M.
A1 Mittal, S.
A1 Wu, Z.
A1 Neelavalli, J.
A1 Cheng, Y.-C.N.
YR 2009
UL http://www.ajnr.org/content/30/1/19.abstract
AB SUMMARY: Susceptibility-weighted imaging (SWI) is a new neuroimaging technique, which uses tissue magnetic susceptibility differences to generate a unique contrast, different from that of spin density, T1, T2, and T2*. In this review (the first of 2 parts), we present the technical background for SWI. We discuss the concept of gradient-echo images and how we can measure local changes in susceptibility. Armed with this material, we introduce the steps required to transform the original magnitude and phase images into SWI data. The use of SWI filtered phase as a means to visualize and potentially quantify iron in the brain is presented. Advice for the correct interpretation of SWI data is discussed, and a set of recommended sequence parameters for different field strengths is given.